Assistant coach Corrado Verdelli, who has enjoyed success with Inter's youth team, takes charge temporarily.
Barcelona, AC Milan and Arsenal can all book places in the knockout stages of the Champions League with wins on Tuesday.
AC Milan coach Carlo Ancelotti was pleased with his side's performance in recovering from 1-0 down with 10 men to beat Lazio 2-1 at Rome's Olympic Stadium on Sunday.
David Beckham's request for a permanent move from Los Angeles Galaxy to AC Milan, where he has been on loan, fizzled out on Friday when the Italian club failed to raise their bid for the player.
Inter Milan have signed Argentina midfielder Ever Banega on a three-year contract, the Serie A club said on Wednesday. The 28-year-old, who helped Sevilla lift their third straight Europa League title last season, scored five league goals in 25 appearances as they finished seventh in La Liga.
AC Milan still hope to sign David Beckham from Los Angeles Galaxy permanently and view the deadline imposed for a deal by Major League Soccer as a "tactic," chief executive Adriano Galliani said on Saturday.
Chelsea's England midfielder Frank Lampard is a transfer target for Serie A champions Inter Milan, club president Massimo Moratti said on Monday. Lampard is one of several Chelsea players to have been linked with a move to the San Siro since the London club's former boss Jose Mourinho was appointed Inter coach earlier this month.
David Beckham said on Friday he will go on AC Milan's tour of Dubai during Italian Serie A's winter break but again reiterated he would be returning to Los Angeles Galaxy once his short loan spell is over. Beckham, who is joining Milan to keep his fitness up and stay in the England picture during the US close season, will not be able to play officially for the Rossoneri until January.
The following is the draw for the Champions League last 16 which was held in Nyon on Monday:
Mathieu Flamini scored and was sent off as AC Milan were held 1-1 by Napoli in a third-versus-second battle in Serie A on Sunday while Inter Milan were on the wrong end of another controversial penalty in a 2-0 loss at Cagliari.
Inter Milan a laboured 1-0 win over promoted Lecce while city rivals AC Milan also had to work hard to secure a 2-1 victory at Reggina in the Serie A.
Hard running, hard tackling and an ever-visible aggression and determination characterise Gennaro Gattuso.
The Brazilian World Cup winner is free to find a new club when the transfer market re-opens.
Ronaldo's replacement Dybala scored in the 77th minute with a goal the Portuguese would have been proud of. After a quick exchange of passes, the Argentine twisted past Alessio Romagnoli and beat Gianluigi Donnarumma with a right foot shot.
AC Milan coach Carlo Ancelotti held a meeting with chief executive Adriano Galliani and club staff on Monday to discuss the Serie A side's poor start to the season.
In other Champions League matches, Manchester United beat Scottish champions Rangers while Chelsea impressed while beating Lazio.
Atalanta came from behind to beat AC Milan 2-1 and move up to sixth place in the Italian Serie A.
Gus Atkinson scored a superb maiden century as England's lower order collected quick runs against a ragged Sri Lanka bowling attack to post 427
IMAGES from Day 1 of the second Test between England and Sri Lanka, at Lord's, on Thursday.
Arsenal midfielder Mathieu Flamini will join AC Milan on a four-year deal, the Serie A club said on Monday. The 24-year-old Frenchman, who signed for Arsenal from Olympique Marseille in 2004, will move on a free transfer with his contract at the Premier League club soon expiring.
David Beckham wants to stay at AC Milan after his loan from Los Angeles Galaxy finishes on March 9, the Serie A club's chief executive, Adriano Galliani, said on Tuesday.
Former Italian Prime Minister Silvio Berlusconi said on Saturday more time is needed to seal an accord over a sale of a stake in AC Milan with Thai businessman Bee Taechaubol but said he could retain control of the soccer club.
Players at Serie A champions Juventus were among those who returned to training following the coronavirus stoppage on Tuesday. The Italian government on Sunday confirmed that professional athletes in both individual and team sports could start training.
Substitute Alexandre Pato netted a superb winner after Robinho had opened the scoring using the top of his arm as Serie A leaders AC Milan ground out a precious 2-1 win at Chievo on Sunday.
Zlatan Ibrahimovic has yet to declare eternal love for AC Milan but he is already striking blows at former club and last term's treble winners Inter Milan.
IMAGES from the Europa League matches played on Thursday
Italy striker Mario Balotelli has joined Liverpool from AC Milan on a "long-term" deal, the Premier League club said on Monday.
Ronaldinho has agreed initial terms with AC Milan and the Serie A club will now speak to Barcelona about a deal, Milan and the player's agent have said. The 28-year-old Brazilian has had a difficult few months at the Nou Camp because of injury and loss of form and a move has long been mooted. The forward is out for the rest of the campaign with a leg injury and a transfer can not officially go through until the end of the season.
AC Milan have denied British media reports that they are about to sell Brazil playmaker Kaka to Chelsea. The Guardian newspaper had reported on Saturday that negotiations for a 100 million euro ($158.5 million) transfer were at an advanced stage after talks this week.
Later on Monday, Lukaku's brace helped Inter to a win over Napoli, taking them atop the standings on goal difference from Juventus.
AC Milan striker Ronaldo suffered a thigh injury in training on Friday and is doubtful for Sunday's Serie A match with Fiorentina.
Serie A leaders AC Milan dropped two precious points by drawing 1-1 at Catania on Saturday in another match featuring controversy over a goalline clearance.
Goekhan Inler took advantage of dreadful AC Milan defending to give Udinese a deserved 1-0 win in their Italian Cup quarter-final on Wednesday.
Two Wayne Rooney headers midway through the second half gave Manchester United a slightly fortunate 3-2 win at AC Milan in their pulsating Champions League last 16 first leg on Tuesday. Seven-times champions Milan, who had never lost to United at home or over two legs, were quickly ahead when Ronaldinho's volley deflected in off Michael Carrick following a free kick from former United midfielder David Beckham.
UEFA delayed a decision until next week on whether to allow AC Milan to participate in this season's Champions League.
Inter Milan have appointed former Ajax Amsterdam manager Frank de Boer as their new head coach on a three-year contract replacing Roberto Mancini.
The Argentine striker was taken on loan on a two-year deal from Chelsea.
Last week's Champions League first leg quarter-final in Lyon ended goalless, leaving Milan needing a victory as a scoring draw would send the French side through on the 'away goals' rule.
